Using third-party tools like Cheat Engine on Steam generally won't trigger a VAC ban for single-player games, but always use caution and disable them before launching any multiplayer title. Kingdom Come Deliverance - Page 23 - FearLess Cheat Engine

Use too many cheats at once, and the game might stutter, crash, or give you a look of medieval disappointment. Also, some quest triggers break if you spawn quest items too early. So, you know… don’t cheat too stupidly.