The culprit is almost always the . When you reinstall your operating system, move your PES 2010 installation folder to a new PC, or attempt a manual "no-disc" installation, the required registry entries are missing. Without them, the game might launch to a black screen, crash immediately, display an uninstall error, or fail to recognize patches.
, the operating system uses a redirection layer for backward compatibility. 32-bit applications like PES 2010 are redirected to: HKEY_LOCAL_MACHINE\SOFTWARE\WOW6432Node\KONAMIPES2010